Symbol
Name
ID

Dcaf17
DDB1 and CUL4 associated factor 17
MGI:1923013

Phenotype annotations related to reproductive system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Hypogonadism	Hypergonadotropic hypogonadism	Hypogonadotropic hypogonadism	Micropenis	Decreased testicular size	Hypoplasia of the fallopian tube	Streak ovary	Hypoplasia of the uterus	Premature ovarian insufficiency	Abnormal spermatogenesis
Disease(s) Associated with DCAF17
Woodhouse-Sakati syndrome

Mouse Phenotypes

reproductive system phenotype

abnormal sperm flagellum morphology

abnormal sperm midpiece morphology

oligozoospermia

teratozoospermia

abnormal sperm head morphology

abnormal acrosome morphology

abnormal acrosome assembly

globozoospermia

detached acrosome

abnormal sperm nucleus morphology

abnormal manchette morphology

abnormal manchette perinuclear ring morphology

elongated manchette

increased male germ cell apoptosis

asthenozoospermia

abnormal male meiosis

abnormal spermatogenesis

male infertility

Availability

Mouse Genotype

Dcaf17^tm1.1Assi/Dcaf17^tm1.1Assi

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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